HRH2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52099PU-N

HRH2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HRH2 Antibody (Center) in Uterus cell line lysates (35ug/lane). This demonstrates the HRH2 antibody detected the HRH2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 188-218 amino acids from the Central region of human Histamine H2 receptor
• Specificity: This antibody recognizes Human Histamine H2 receptor (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: histamine receptor H2
• Database Link:
  Entrez Gene 3274 Human
  UniProt ID P25021
• Background:
  Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: H2R, HRH2, Gastric receptor I
• Note: Molecular Weight: 40098 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction