Frizzled 2 (FZD2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP51747PU-N

Frizzled 2 (FZD2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FZD2 / Frizzled-2 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the FZD2 antibody detected the FZD2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 533-563 amino acids from the C-terminal region of Human FZD2 / Frizzled-2
• Specificity: This antibody recognizes Human FZD2 / Frizzled-2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: frizzled class receptor 2
• Database Link:
  Entrez Gene 2535 Human
  UniProt ID Q14332
• Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.
• Synonyms: Fz-2, hFz2, FzE2
• Note: Molecular Weight: 63554 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway