Destrin (DSTN) (Center) Rabbit Polyclonal Antibody

CAT#: AP51327PU-N

Destrin (DSTN) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Destrin Antibody in MCF-7 cell line lysates (35ug/lane). DSTN (arrow) was detected using the purified Pab.

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  Western blot analysis of DSTN (arrow) using Destrin Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DSTN gene.

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with Destrin Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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  Flow cytometry analysis of MCF-7 cells using Destrin Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 77~106 amino acids from the Center region of Human Destrin.
• Specificity: This antibody recognizes Human Destrin (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: destrin, actin depolymerizing factor
• Database Link:
  Entrez Gene 11034 Human
  UniProt ID P60981
• Background: DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This protein encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
• Synonyms: DSTN, ACTDP, DSN, ADF
• Note: Molecular Weight: 18506 Da