Desmoglein 3 (DSG3) (N-term) Rabbit Polyclonal Antibody

CAT#: AP51324PU-N

Desmoglein 3 (DSG3) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Desmoglein-3 Antibody (N-term) in WiDr cell line lysates (35ug/lane). This demonstrates the DSG3 antibody detected the DSG3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of Human Desmoglein-3
• Specificity: This antibody recognizes Human Desmoglein-3 (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: desmoglein 3
• Database Link:
  Entrez Gene 1830 Human
  UniProt ID P32926
• Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
• Synonyms: DSG3, CDHF6, PVA, 130 kDa pemphigus vulgaris antigen
• Note: Molecular Weight: 107533 Da