DDX11 (Center) Rabbit Polyclonal Antibody

CAT#: AP51215PU-N

DDX11 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DDX11 Antibody (Center) in mouse Neuro-2a cell line lysates (35ug/lane). This demonstrates the DDX11 antibody detected the DDX11 protein (arrow).

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  Flow cytometric analysis of Neuro-2a cells using DDX11 Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 663-691 amino acids from the Central region of Human DDX11.
• Specificity: This antibody recognizes Human and Mouse DEAD box protein 11 (Center).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: DEAD/H-box helicase 11
• Database Link:
  Entrez Gene 1663 Human
  UniProt ID Q96FC9
• Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability.
• Synonyms: DEAD/H box protein 11, CHL1, CHLR1, KRG2, KRG-2, DEAD box protein 11
• Note: Molecular Weight: 108313 Da

Reference Data

• Protein Families: Stem cell - Pluripotency