CEBP Alpha (CEBPA) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50847PU-N

CEBP Alpha (CEBPA) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CEBPA Antibody (C-term) in mouse liver tissue lysates (35ug/lane). CEBPA (arrow) was detected using the purified Pab.

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  CEBPA Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 310~339 amino acids from the C-terminal region of human CEBPA
• Specificity: This antibody reacts to CEBPA.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 37561 Da
• Gene Name: CCAAT/enhancer binding protein alpha
• Database Link:
  Entrez Gene 12606 MouseEntrez Gene 1050 Human
  UniProt ID P49715
• Background: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
• Synonyms: C/EBP alpha

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Acute myeloid leukemia, Pathways in cancer