ACCN4 (ASIC4) (N-term) Rabbit Polyclonal Antibody

CAT#: AP50045PU-N

ACCN4 (ASIC4) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ACCN4 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ACCN4 antibody detected the ACCN4 protein (arrow)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 22-52 amino acids from the N-terminal region of human ACCN4
• Specificity: This antibody reacts to ASIC4 / ACCN4.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: acid sensing ion channel subunit family member 4
• Database Link:
  Entrez Gene 55515 Human
  UniProt ID Q96FT7
• Background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
• Synonyms: ACCN4; BNAC4
• Note: Molecular Weight: 70105 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other