CD31 (PECAM1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP31323PU-N

CD31 (PECAM1) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of extracts from Jurkat cells, using PECAM-1 Antibody. The lane on the right is treated with the synthesized peptide.

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  Human Tonsil, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence analysis of HeLa cells, using PECAM-1 Antibody. The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/20000.
  Immunofluorescence: 1/100 - 1/500.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human PECAM-1.
  Epitope: C-Terminus.
• Specificity: This antibody detects endogenous levels of total PECAM-1 protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: platelet and endothelial cell adhesion molecule 1
• Database Link:
  Entrez Gene 18613 MouseEntrez Gene 5175 Human
  UniProt ID P16284
• Background: CD31 (PECAM1) is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
• Synonyms: PECAM-1, EndoCAM, GPIIA'

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration