alpha smooth muscle Actin (ACTA2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP31046PU-N

alpha smooth muscle Actin (ACTA2) (N-term) rabbit polyclonal antibody, Purified

Product Images

Human Lung, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/100.
• Reactivities: Bovine, Chicken, Human, Monkey, Mouse, Rabbit, Rat, Baboon
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide from N-terminus of Human alpha smooth muscle isoform of Actin
• Specificity: This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells. Actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial) are not labeled.
• Formulation: 10 mM PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
  Stabilizer: BSA
  Preservative: 0.09% Sodium Azide
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: actin, alpha 2, smooth muscle, aorta
• Database Link:
  Entrez Gene 11475 MouseEntrez Gene 81633 RatEntrez Gene 100427024 MonkeyEntrez Gene 59 Human
  UniProt ID P62736
• Background: Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.
• Synonyms: ACTSA, ACTVS, Alpha-actin-2

Reference Data

• Protein Pathways: Vascular smooth muscle contraction