Kcnip1 (12-22) Rabbit Polyclonal Antibody

CAT#: AP26424AF-L

Kcnip1 (12-22) rabbit polyclonal antibody, Azide Free

Product Images

Western blot analysis of extracts from mouse brain using anti-kchip1 rabbit whole antiserum.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA: Dilute the antibody approx. 1:300,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate.
  Western blot: Dilute approx. 1:4,000 to detect the 27kDa Kchip1 in mouse brain extract.
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A synthetic peptide derived from the amino sequence amino acid 12-22 of mouse Kchip1, conjugated with KLH
• Specificity: This antibody is reactive to the 27kDa Kchip1 in Mouse and other species with consensus Kchip1 sequence.
• Formulation: 0.01M PBS, pH 7.4
  State: Azide Free
  State: Lyophilized Ig fraction
• Reconstitution Method: Restore with double distilled water to adjust the final concentration to 1.00 mg/ml.
• Purification: Protein G affinity
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 month or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Kv channel-interacting protein 1
• Database Link:
  Entrez Gene 70357 Mouse
  UniProt ID Q9JJ57
• Background: KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.
• Synonyms: KCHIP1