TRF2 (TERF2) Goat Polyclonal Antibody

CAT#: AP22995PU-N

TRF2 (TERF2) goat polyclonal antibody, Aff - Purified

Product Images

Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human, Bovine, Bat, Canine, Equine, Monkey, Porcine
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from human TERF2 / TRF2
• Specificity: This antibody reacts to Telomeric Repeat Binding Factor 2 (TERF2).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: telomeric repeat binding factor 2
• Database Link:
  Entrez Gene 7014 Human
  UniProt ID Q15554
• Background: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection.
• Synonyms: TRBF2, TRF2

Reference Data

• Protein Families: Transcription Factors