MRPS36 Rabbit Polyclonal Antibody

CAT#: AP21194PU-N

MRPS36 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of MRP-S36 antibody (Cat.-No.: AP21194PU-N) in extracts from HepG2 cells.

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  Immunohistochemistry (IHC) analyzes of MRP-S36 antibody (Cat.-No.: AP21194PU-N) in paraffin-embedded human prostate carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of MRP-S36 protein.
  (region surrounding Val36)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 15 kDa
• Gene Name: mitochondrial ribosomal protein S36
• Database Link:
  Entrez Gene 92259 Human
  UniProt ID P82909
• Background: Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S36 (mitochondrial ribosomal protein S36), is a 103 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-S36 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
• Synonyms: S36mt, DC47