GAS1 Rabbit Polyclonal Antibody

CAT#: AP21186PU-N

GAS1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Gas1 antibody (Cat.-No.: AP21186PU-N) in extracts from MCF-7 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Gas1 protein.
  (region surrounding Arg274)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 36 kDa
• Gene Name: growth arrest specific 1
• Database Link:
  Entrez Gene 14451 MouseEntrez Gene 2619 Human
  UniProt ID P54826
• Background: Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas 1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.
• Synonyms: Growth arrest-specific protein 1, GAS-1

Reference Data

• Protein Pathways: Hedgehog signaling pathway