Integrin Linked Kinase (ILK) Rabbit Polyclonal Antibody

CAT#: AP21113PU-N

Integrin Linked Kinase (ILK) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of ILK antibody (Cat.-No.: AP21113PU-N) in extracts from rat liver cells.

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  Immunohistochemistry (IHC) analyzes of ILK antibody (Cat.-No.: AP21113PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of ILK protein.
  (region surrounding Pro240)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 51 kDa
• Gene Name: integrin linked kinase
• Database Link:
  Entrez Gene 16202 MouseEntrez Gene 170922 RatEntrez Gene 3611 Human
  UniProt ID Q13418
• Background: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin linked kinase (ILK), interacts with the cytoplasmic domain of beta 1 Integrin. ILK encodes a predicted 451 amino acid protein, with an apparent molecular weight of 59 kDa. The ILK protein is a serine/threonine protein kinase with 4 ankyrin like repeats. ILK regulates integrin mediated signal transduction.
• Synonyms: ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Endometrial cancer, Focal adhesion, PPAR signaling pathway