Myeloid leukemia factor 1 (MLF1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17562PU-N

Myeloid leukemia factor 1 (MLF1) (N-term) rabbit polyclonal antibody


USD 580.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of human MLF1
Specificity This antibody reacts to Myeloid leukemia factor 1.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid purfied Ig
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name myeloid leukemia factor 1
Background MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Synonyms MLF1
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.