PBP (PEBP1) (Center) Rabbit Polyclonal Antibody

CAT#: AP15048PU-N

PBP (PEBP1) (Center) rabbit polyclonal antibody, Purified

Product Images

(LEFT) Western blot analysis of anti-PBP Antibody (Center) Antibody (Center) in Hela cell line lysates (35ug/lane). PBP (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of anti-PBP Antibody (Center) in mouse NIH-3T3 tissue lysates (35ug/lane). PBP (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human PBP.
• Specificity: This antibody reacts to PBP.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: phosphatidylethanolamine binding protein 1
• Database Link:
  Entrez Gene 5037 Human
  UniProt ID P30086
• Background: PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
• Synonyms: PEBP-1, PEBP, Prostatic-binding protein, PBP, Raf kinase inhibitor protein, HCNPpp