IL3RB (CSF2RB) pTyr766 Rabbit Polyclonal Antibody

CAT#: AP12630PU-N

IL3RB (CSF2RB) pTyr766 rabbit polyclonal antibody, Aff - Purified

Product Images

(LEFT) The anti-Phospho-IL3R-Y766 Pab is used in Western blot to detect Phospho-IL3R-Y766 in mouse heart tissue lysate. (RIGHT) Dot blot analysis of anti-hIL3R-pY766 Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Dot Blot: 1/500.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y766 of human IL3R.
• Specificity: This antibody detects IL3R pTyr766.
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: colony stimulating factor 2 receptor beta common subunit
• Database Link:
  Entrez Gene 1439 Human
  UniProt ID P32927
• Background: IL3R (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective IL3R has been reported to be associated with protein alveolar proteinosis (PAP). PAP is an autosomal recessive fatal respiratory disease.
• Synonyms: IL3RB, IL5RB, GM-CSF-RB
• Note: Molecular weight: 97336 Da