PADI4 (C-term) Rabbit Polyclonal Antibody

CAT#: AP12282PU-N

PADI4 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-PAD4 Pab in 293 cell line lysate. PAD4 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PAD4.
• Specificity: This antibody detects PAD4 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: peptidyl arginine deiminase 4
• Database Link:
  Entrez Gene 23569 Human
  UniProt ID Q9UM07
• Background: PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.
• Synonyms: PDI4, PAD4, PDI5, PADI5, PADI-H, HL-60 PAD
• Note: Molecular weight: 74095 Da