Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody

CAT#: AP10441PU-N

Transglutaminase 2 (TGM2) rabbit polyclonal antibody, Purified

Product Images

Western Blot (10% gel) with TGM2 antibody Cat.-No AP10441PU-N

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Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/200-1/1000.
  Immunohistochemistry: 1/200-1/2000.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A 15 residue synthetic peptide derived from specific domain of Human TG2 protein (tTG)
• Specificity: Reacts with Human 77 kDa TGM2 protein.
  This antibody does not cross reacts with Guinea Pig or any isoformes.
• Formulation: 0.1M Tris, 0.1M Glycine and 2% Sucrose
  State: Purified
  State: Lyophilized purified powder
  Preservative: None
• Reconstitution Method: Restore in distilled water.
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Prior to reconstitution store the antibody at -20°C.
  Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: transglutaminase 2
• Database Link:
  Entrez Gene 7052 Human
  UniProt ID P21980
• Background: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
• Synonyms: TGase C, TGase-H, Tissue transglutaminase