Tyrosine Hydroxylase (TH) pSer19 Rabbit Polyclonal Antibody
CAT#: AP09482PU-S
Tyrosine Hydroxylase (TH) pSer19 rabbit polyclonal antibody, Aff - Purified
Size: 100 ul
Other products for "Tyrosine Hydroxylase"
Specifications
Product Data | |
Applications | IF |
Recommended Dilution | Immunofluorescence: 1/100~1/200. |
Reactivities | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q). |
Specificity | Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. |
Conjugation | Unconjugated |
Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | tyrosine hydroxylase |
Database Link | |
Background | Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease |
Synonyms | Tyrosine 3-hydroxylase, TYH |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Parkinson's disease, Tyrosine metabolism |
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