Tyrosine Hydroxylase (TH) pSer19 Rabbit Polyclonal Antibody

CAT#: AP09482PU-N

Tyrosine Hydroxylase (TH) pSer19 rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using Tyrosine Hydroxylase pSer19 Antibody (Red).

Specifications

Product Data

• Applications: IF
• Recommended Dilution: Immunofluorescence: 1/100~1/200.
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Serine19 (A-V-Sp-E-Q).
• Specificity: Antibody AP09482PU detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at Serine 19.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: tyrosine hydroxylase
• Database Link:
  Entrez Gene 25085 Rat
  UniProt ID P07101
• Background: Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease
• Synonyms: Tyrosine 3-hydroxylase, TYH

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Parkinson's disease, Tyrosine metabolism