Pebp1 Rabbit Polyclonal Antibody

CAT#: AP08722SU-N

Pebp1 rabbit polyclonal antibody, Serum

Product Images

Figure 1. Western blot of rat brain lysate showing the specific immunolabeling of the ~22k PEBP protein.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/1000.
• Reactivities: Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Native PEBP protein purified from rat.
• Specificity: This antibody recognizes the ~22k PEBP protein in Western blots.
• Formulation: State: Serum
  State: Neat Serum.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: phosphatidylethanolamine binding protein 1
• Database Link:
  Entrez Gene 29542 Rat
  UniProt ID P31044
• Background: Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006)
• Synonyms: PEBP-1, PEBP, Prostatic-binding protein, PBP, Raf kinase inhibitor protein, HCNPpp