CD61 (ITGB3) Rabbit Polyclonal Antibody

CAT#: AP08064PU-N

CD61 (ITGB3) rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 1. Western blot analysis of extract from HUVEC cells untreated or treated with EGF (200ng/ml, 15min), using integrin beta 3 antibody AP08064PU (Lane 1 and 2) and Integrin beta 3 (phospho-Tyr785) antibody AP02524PU (Lane 3 and 4).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot (1/500-1/1000).
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Integrin beta 3 around the phosphorylation site of Tyrosine 785 (I-T-YP-R-G).
• Specificity: Integrin beta 3 Antibody AP08064PU detects endogenous levels of total Integrin beta 3 protein.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: integrin subunit beta 3
• Database Link:
  Entrez Gene 3690 Human
  UniProt ID P05106
• Background: Human Integrin beta 3 (CD61) antigen is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The platelet glycoprotein is the integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex.
• Synonyms: Integrin beta-3, GP3A, GPIIIa