Stefin B (CSTB) Rabbit Polyclonal Antibody

CAT#: AP06334PU-N

Stefin B (CSTB) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Stefin B antibody in extracts from A549 cells.

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  Immunohistochemistry (IHC) analyzes of Stefin B antibody in paraffin-embedded Human breast carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 51-100 of Human Cystatin B.
• Specificity: This antibody detects endogenous levels of Stefin B protein.
  (region surrounding asn84)
• Formulation: Phosphate Buffered Saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 11 kDa
• Gene Name: cystatin B
• Database Link:
  Entrez Gene 25308 RatEntrez Gene 1476 Human
  UniProt ID P04080
• Background: Cystatin A (also designated STF1, STFA, stefin A or cystatin AS) and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with Papain and the cathepsins B, H and L. Cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.
• Synonyms: Stefin-B, CPI-B, CSTB, CST6, STFB