FBXW7 Rabbit Polyclonal Antibody
Other products for "FBXW7"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot (1-5 µg/ml). |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide dervied from the human FBXW7 protein |
Specificity | This antibody detects FBXW7, widely expressed in most tissues. |
Formulation | Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | F-box and WD repeat domain containing 7 |
Database Link | |
Background | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. |
Synonyms | FBW7, FBX30, SEL10, Archipelago homolog, hAgo, SEL-10, hCDC4 |
Reference Data |
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in shipping.