PPP2R2B Rabbit Polyclonal Antibody

CAT#: AP05043PU-N

PPP2R2B rabbit polyclonal antibody, Purified

Product Images

PP2 A/B western blot of total rat brain extract. (+) or (-) indicates present of blocking peptide or control peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunoblotting: 1/500-1/1,000.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Gly-Glu-Glu-Asp-Ile-Asp-THr-Arg-Lys-Ile-Asn-Asn-Ser-Phe-COOH. This peptide antibody corresponds to N-terminal peptide of PP2A/Bb regulatory subunit having a MW of 53kDa. The sequence used is amino acid 2-14.
• Specificity: This antibody reacts to serine/threonine protein phosphatase 2A/B beta. Minimal cross reactivity against 2A/Bg .
• Formulation: PBS with 0.08% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig (0.2µm sterile filtered)
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: protein phosphatase 2 regulatory subunit Bbeta
• Database Link:
  Entrez Gene 60660 RatEntrez Gene 72930 MouseEntrez Gene 5521 Human
  UniProt ID Q00005
• Background: PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.
• Synonyms: PP2A subunit B B-beta isoform, B55-beta isoform, PR55-beta isoform, R2-beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Tight junction