PTPN11 / PTP2C Rabbit Polyclonal Antibody

CAT#: AP02796PU-S

PTPN11 / PTP2C rabbit polyclonal antibody, Aff - Purified

Product Images

Western Blot analysis of extracts from 3T3 cells using SHP-2 antibody

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  Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using SHP-2 antibody.

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  Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2 antibody (Red).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500~1/1000.
  Immunofluorescence: 1/100~1/200.
  Immunohistochemistry on Paraffin-Embedded Sections: 1/50~1/100.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human SHP-2 around the phosphorylation site of Tyrosine 542 (H-E-Yp-T-N).
• Specificity: This antibody detects endogenous levels of total PTPN11/SHP-2 protein.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: protein tyrosine phosphatase, non-receptor type 11
• Database Link:
  Entrez Gene 5781 Human
  UniProt ID Q06124
• Background: SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
• Synonyms: SHPTP2, PTP-1D, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3