FOXO4 Rabbit Polyclonal Antibody
Other products for "FOXO4"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Suitable for use in Western blot (1:500-1:1000) and Immunohistochemistry (1:50-1:100). |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-Sp-M-D). |
Specificity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. AFX antibody AP02683PU detects endogenous levels of total AFX protein. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Immunoaffinity chromatography. |
Conjugation | Unconjugated |
Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | forkhead box O4 |
Database Link | |
Background | FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. |
Synonyms | Forkhead box protein O4 |
Reference Data |
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