CGRP (CALCB) Goat Polyclonal Antibody

CAT#: AP02066SU-N

CGRP (CALCB) goat polyclonal antibody, Serum

Specifications

Product Data

• Applications: R
• Recommended Dilution: RIA (1/3,000).
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic Human Calcitonin Gene-related Peptide 2, bTG-conjugated
• Specificity: This antibody detects Calcitonin Gene-related Peptide.
  There were no cross reactivities obtained with Human and Salmon Katacalcin and Calcitonin.
• Formulation: State: Serum
  State: Lyophilized serum
• Reconstitution Method: Restore in aqua bidest to initial volume.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: calcitonin related polypeptide beta
• Database Link:
  Entrez Gene 797 Human
  UniProt ID P10092
• Background: CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
• Synonyms: Calcitonin gene-related peptide 2, Beta-type CGRP, CALC2
• Note: LocusID: 797