CHSY3 Rabbit Polyclonal Antibody

CAT#: AP01393PU-N

CHSY3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of CHSY2 antibody (Cat.-No.: AP01393PU-N) in extracts from LOVO cells

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  Immunohistochemistry (IHC) analyzes of CHSY2 antibody (Cat.-No.: AP01393PU-N) in paraffin-embedded human cervix carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 640-690 of Human CHSY2.
• Specificity: This antibody detects endogenous levels of CHSY2 protein. (region surrounding Arg671)
• Formulation: PBS, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 85 kDa
• Gene Name: chondroitin sulfate synthase 3
• Database Link:
  Entrez Gene 78923 MouseEntrez Gene 291577 RatEntrez Gene 337876 Human
  UniProt ID Q70JA7
• Background: Chondroitin sulfate synthases (CHSYs) synthesize chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to various of core protein families and regulate many biologic processes, including extracellular matrix deposition, cell proliferation and recognition, and morphogenesis. The CHSY family includes CHSY1, CHSY2 and CHSY3. CHSY1 and CHSY3 display both glucuronyltransferase and N-acetylgalactosaminyltransferase activities, while CHSY2 is required for chondroitin polymerizing activity. CHSY2 localizes to the Golgi apparatus and is expressed ubiquitously, with highest expression observed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
• Synonyms: Chondroitin sulfate synthase 3, Chondroitin synthase 2, CHSY2, CSS3, ChSy-2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Chondroitin sulfate biosynthesis, Metabolic pathways