CD153 (TNFSF8) Rabbit Polyclonal Antibody
CD153 (TNFSF8) rabbit polyclonal antibody, Aff - Purified
|Applications||ELISA, IF, WB|
|Recommended Dilution||Western blot: 1/500 - 1/1000.
Immunofluorescence: 1/50 - 1/200.
|Immunogen||Synthetic peptide, corresponding to amino acids 80-130 of Human CD30-L.|
|Specificity||This antibody detects endogenous levels of CD30-L protein.
(region surrounding Gln103)
|Formulation||Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction (>95% pure by SDS-PAGE)
Preservative: 0.05% Sodium Azide
|Purification||Affinity-Chromatography using epitope-specific immunogen|
|Storage||Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Predicted Protein Size||~ 38 kDa|
|Background||The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.|
|Synonyms||TNFSF8, CD30 Ligand, CD30LG, CD30-L|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.