PDE10A Rabbit Polyclonal Antibody

CAT#: AP00661SU-N

PDE10A rabbit polyclonal antibody, Serum

Product Images

Figure 1. Western blot using AP00661SU-N (1/20,000) against lysate from COS cells transfected with the indicated Human PDE isoform.

Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: Western blot.
  Immunoprecipitation.
  Immunohistochemistry.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Designed from the C-terminal region common to the 10A enzyme
• Specificity: The antibody selectively detects proteins corresponding to the PDE10A enzyme (Figure 1)
• Formulation: State: Serum
  State: Liquid Diluted Serum
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -80°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: phosphodiesterase 10A
• Database Link:
  Entrez Gene 10846 Human
  UniProt ID Q9Y233
• Background: Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling.
  The PDE10 enzyme belongs to a family of PDEs that hydrolyse both cAMP and cGMP.
• Synonyms: Phosphodiesterase 10A, HSPDE10A