Neuroligin 4 (782-945, Intracell. Dom.) Mouse Monoclonal Antibody [Clone ID: S98-7]

CAT#: AM60051PU-N

Neuroligin 4 (782-945, Intracell. Dom.) mouse monoclonal antibody, clone S98-7, Purified

Specifications

Product Data

• Clone Name: S98-7
• Applications: IF, WB
• Recommended Dilution: Western blot: 1/1000; 1 μg/ml was sufficient for detection of Neuroligin-4 in 20 μg of mouse brain lysate by colorimetric immunoblot analysis using HRP conjugated secondary antibody.
  Immunocytochemistry.
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 782-945 (intracellular, C-terminus) of mouse Neuroligin 4.
• Specificity:
  This antibody detects Neuroligin 4; ~125-130 kDa.
  ( ~45% identity with Neuroligin-1, -2 and -3)
• Formulation: PBS pH 7.4, 50% Glycerol, 0.09% Sodium azide
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Protein G chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Database Link:
  UniProt ID B0F2B4
• Background: The Nlgn4l gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.
• Synonyms: Neuroligin-4*, Neuroligin 4-like, NL-4, Nlgn4l, Nlgn4, Nlgn4x