CD64 (FCGR1A) Mouse Monoclonal Antibody [Clone ID: AT37F7]

CAT#: AM50348PU-N

CD64 (FCGR1A) mouse monoclonal antibody, clone AT37F7, Purified

Product Images

The cell lysates of Jurkat and U937 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human FCGR1A antibody (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT37F7
• Applications: ELISA, WB
• Recommended Dilution: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant human FCGR1A (16-292aa) purified from E.coli.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Fc fragment of IgG receptor Ia
• Database Link:
  Entrez Gene 2209 Human
  UniProt ID P12314
• Background: High affinity immunoglobulin gamma Fc receptor I (FCGR1A) is a protein that in humans is encoded by the FCGR1A gene. Also, This protein is known as CD64, belongs to the immunoglobulin superfamily. It is a high-affinity Fc-gamma receptor. They are playing a role in both innate and adaptive immune responses. They have been shown to interact with FCAR. The FcgRI binds the Fc portion of IgG and causes activation of the host cell via an intercellular ITAM motif.
• Synonyms: IgG Fc receptor I, FcgammaRIa, FcRI, Fc-gamma RI, Fc-gamma RIA

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Fc gamma R-mediated phagocytosis, Hematopoietic cell lineage, Systemic lupus erythematosus