FGF 23 (FGF23) Mouse Monoclonal Antibody [Clone ID: FGF23/638]
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Specifications
Product Data | |
Clone Name | FGF23/638 |
Recommended Dilution | ELISA: Use BSA free Antibody for coating. Functional Studies: Use BSA and Azide free Antibody. Positive Control: Human PBL cells or brain tumors. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant Human FGF23 protein. |
Specificity | Recognizes FGF23 (Fibroblast Growth Factor 23). Cellular Localization: Secreted (extracellular). |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 12-32 kDa |
Gene Name | fibroblast growth factor 23 |
Database Link | |
Background | Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3. |
Synonyms | Fibroblast growth factor 23, FGF-23, Phosphatonin, HYPF |
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