Cd8a Mouse Monoclonal Antibody [Clone ID: OX8-2b]

CAT#: AM32150SU-N

Cd8a mouse monoclonal antibody, clone OX8-2b, Supernatant

Specifications

Product Data

• Clone Name: OX8-2b
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometric analysis of Rat lymphocytes, especially in multicolor stainings.
  Immunohistochemistry on Fresh Frozen Sections.
  Immunohistochemistry on Formalin-Fixed Paraffin-Embedded Sections: Citric acid pretreatment is recommended.
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: The antibody binds to a Rat strain-independent epitope of the alpha-chain of CD8, present on the CD8-positive subsets of T cells and NK cells.
• Formulation: State: Supernatant
  State: Hybridoma Culture Supernatant
  Preservative: 0.05% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for Two months or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD8a molecule
• Database Link:
  Entrez Gene 24930 Rat
  UniProt ID P07725
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8 alpha chain, CD8A, MAL