TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: Mab11]

CAT#: AM26711AC-N

TNF alpha (TNF) mouse monoclonal antibody, clone Mab11, APC

Product Images

Intracellular staining of activated human peripheral blood with anti-TNF alpha (MAb11) APC.

Specifications

Product Data

• Clone Name: Mab11
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human, Porcine, Primate
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human TNF-alpha
• Specificity: This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
• Formulation: Phosphate buffered saline (PBS)
  Label: APC
  State: Liquid purified Ig fraction
  Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
  Preservative: 15 mM sodium azide
  Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
• Conjugation: APC
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: tumor necrosis factor
• Database Link:
  Entrez Gene 7124 Human
  UniProt ID P01375
• Background: TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
• Synonyms: TNF, TNF-a, TNFA, TNFSF2, Cachectin