HIV-1 Nef / BRU (171-190) Mouse Monoclonal Antibody [Clone ID: 2H12 (01-007)]

CAT#: AM26079PU-N

HIV-1 Nef / BRU (171-190) mouse monoclonal antibody, clone 2H12 (01-007), Aff - Purified

Specifications

Product Data

• Clone Name: 2H12 (01-007)
• Applications: ELISA, IHC, WB
• Recommended Dilution: Reacts in ELISA, Western blot and Immunohistochemistry on frozen sections with HIV-1 Nef of BRU, IIIB, and HAN strains. Titer using rNef protein with subtype B a.a. consensus:
  ELISA: 1: 10 000.
  Western blot: 1: 1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody detects HIV-1 Nef (aa 171-190).
  It reacts only with rNef of HIV-1 subtype B and C.
• Formulation: PBS pH 7.4, with 0.09% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Background: HIV is a highly variable virus which mutates very readily. This means there are many different strains of HIV, even within the body of a single infected person. The strains of HIV1 can be classified into three groups: the "major" group M, the "outlier" group O and the "new" group N. These three groups may represent three separate introductions of simian immunodeficiency virus into humans. Group O appears to be restricted to West-Central Africa and group N, discovered in 1998 in Cameroon, is extremely rare. More than 90% of HIV1 infections belong to HIV1 group M.
• Synonyms: HIV1, HIV-I, Human immunodeficiency virus type 1