MCM7 Mouse Monoclonal Antibody [Clone ID: M3]

CAT#: AM20639PU-N

MCM7 mouse monoclonal antibody, clone M3, Purified

Specifications

Product Data

• Clone Name: M3
• Applications: IF, WB
• Recommended Dilution: Western Blot: 0.5 - 1 μg/ml.
  Immunocytochemistry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody reacts to MCM7.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: 0,1 mg/ml (after reconstitution with PBS)
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: minichromosome maintenance complex component 7
• Database Link:
  Entrez Gene 4176 Human
  UniProt ID P33993
• Background: Initiation of DNA replication is a complex process involving the concerted action of many proteins. The chromosome 7-linked gene referred to by Nakatsuru et al. (1995) as MCM2 has been designated MCM7. The MCM2-7 complex is comprised of 6 subunits, MCM2 through MCM7, and is a ring-shaped heterohexameric ATPase involved in DNA replication. MCM7 is located in 7q21.3-q22.1
• Synonyms: CDC47, MCM2, CDC47 homolog, P1.1-MCM3

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Cell cycle, DNA replication