Cytokeratin 5 (KRT5) Mouse Monoclonal Antibody [Clone ID: D5/16 B4]

CAT#: AM10102SU-N

Cytokeratin 5 (KRT5) mouse monoclonal antibody, clone D5/16 B4, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human prostate carcinoma stained with Cytokeratin-5/6 antibody Cat.-No. AM10102SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of basal cells of benign but not tumor glands.

Specifications

Product Data

• Clone Name: D5/16 B4
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Mesothelioma, prostate.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Isolated Cytokeratin-5
• Specificity: Recognizes Cytokeratin 5/6.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: keratin 5
• Database Link:
  Entrez Gene 54474 HumanEntrez Gene 3852 Human
  UniProt ID P13647
• Background: Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification.
• Synonyms: KRT5, Cytokeratin-5, Keratin-5, Keratin 5, CK5, K5