CD59 Mouse Monoclonal Antibody [Clone ID: p282 (H19)]

CAT#: AM08350PU-N

CD59 mouse monoclonal antibody, clone p282 (H19), Purified

Product Images

at 10 ug/ml staining CD59 by Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Placenta Sections).

Specifications

Product Data

• Clone Name: p282 (H19)
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometry: 2 µg/10E6 cells.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
• Reactivities: Human, Monkey, Chimpanzee, Baboon
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody recognizes CD59 Glycoprotein.
• Formulation: PBS, pH 7.2 containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD59 molecule
• Database Link:
  Entrez Gene 966 Human
  UniProt ID P13987
• Background: CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
• Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21, MACIF, MAC-IP, MIRL, HRF20, HRF-20