Cd79b Hamster Monoclonal Antibody [Clone ID: HM79-12]

CAT#: AM08072LE-N

Cd79b hamster monoclonal antibody, clone HM79-12, Low Endotoxin

Specifications

Product Data

• Clone Name: HM79-12
• Applications: FC, IHC, IP, WB
• Recommended Dilution: Flow Cytometry. (Ref.1,2)
  Immunoprecipitation. (Ref.1)
  Immunohistochemistry on Frozen Sections. (Ref.3)
  Western Blotting. (Ref.1)
• Reactivities: Mouse
• Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Specificity: This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa).
• Formulation: PBS without preservatives.
  State: Low Endotoxin
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD79B antigen
• Database Link:
  Entrez Gene 15985 Mouse
  UniProt ID P15530
• Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)
• Synonyms: B29, IGB, B-Cell marker