Cd24a Rat Monoclonal Antibody [Clone ID: 30-F1]

CAT#: AM08069PU-N

Cd24a rat monoclonal antibody, clone 30-F1, Purified

Specifications

Product Data

• Clone Name: 30-F1
• Applications: FC, IP
• Recommended Dilution: Flow Cytometry and Cell Sorting. (Ref.3,4,7-10)
  Immunoprecipitation. (Ref.3)
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2c
• Clonality: Monoclonal
• Specificity: This antibody recognises CD24/Heat Stable Antigen (HSA).
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD24a antigen
• Database Link:
  Entrez Gene 12484 Mouse
  UniProt ID P24807
• Background: CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer.
• Synonyms: X62 heat stable antigen, HSA