Thy1 Rat Monoclonal Antibody [Clone ID: G7]

CAT#: AM08054PU-N

Thy1 rat monoclonal antibody, clone G7, Purified

Specifications

Product Data

• Clone Name: G7
• Applications: FC, FN, IHC
• Recommended Dilution: Flow Cytometry. (Ref.1,10)
  Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10)
  In vitro T Cell Activation. (Ref.1,5,6,9)
  Induction of apoptosis.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2c
• Clonality: Monoclonal
• Specificity: This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A).
  MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7).
  It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: thymus cell antigen 1, theta
• Database Link:
  Entrez Gene 21838 Mouse
  UniProt ID P01831
• Background: CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)
• Synonyms: Thy-1, THY1, CDw90