Collagen IV (COL4A1) Mouse Monoclonal Antibody [Clone ID: 2F11]

CAT#: AM08027PU-N

Collagen IV (COL4A1) mouse monoclonal antibody, clone 2F11, Purified

Specifications

Product Data

• Clone Name: 2F11
• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/2,000-1/8,000.
  Immunohistochemistry: < / = 2 µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody reacts with Human Type IV Collagen.
• Formulation: 100 mM Borate Buffered Saline, pH 8.2.
  No preservatives or amine-containing buffer salts added.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: collagen type IV alpha 1 chain
• Database Link:
  Entrez Gene 1282 Human
  UniProt ID P02462
• Background: Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.
• Synonyms: COL4A1

Reference Data

• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer