CDK9 Mouse Monoclonal Antibody [Clone ID: 1B5A7]

CAT#: AM06623SU-N

CDK9 mouse monoclonal antibody, clone 1B5A7, Ascites

Product Images

Western blot analysis using CDK9 mAb against HEK293 (1) and CDK9 (AA: 178-369)-hIgGFc transfected HEK293 (2) cell lysate.

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  Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

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  Immunohistochemical analysis of paraffin-embedded rectum cancer tissues (left) and placenta tissues (right) using CDK9 mouse mAb with DAB staining.

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  Immunohistochemical analysis of paraffin-embedded brain tissues (left) and esophageal cancer tissues (right) using CDK9 mouse mAb with DAB staining.

Specifications

Product Data

• Clone Name: 1B5A7
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human CDK9 expressed in E. Coli.
  
• Specificity: This antibody reacts to CDK9.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 43 kDa
• Gene Name: cyclin-dependent kinase 9
• Database Link:
  Entrez Gene 1025 Human
  UniProt ID P50750
• Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.
• Synonyms: PITALRE, CDC2L4