GLP1 (GCG) Mouse Monoclonal Antibody [Clone ID: 2F9]

CAT#: AM06563SU-N

GLP1 (GCG) mouse monoclonal antibody, clone 2F9, Ascites

Product Images

Western blot analysis using GCG antibody Cat.-No AM06563SU-N against HEK293 (1) and GCG (AA: 1-180)-hIgGFc transfected HEK293 (2) cell lysate.

Specifications

Product Data

• Clone Name: 2F9
• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human GCG expressed in E. Coli.
• Specificity: Recognizes Glucagon (GCG)
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 21 kDa
• Gene Name: glucagon
• Database Link:
  Entrez Gene 2641 Human
  UniProt ID P01275
• Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.
• Synonyms: GCG