Lipoprotein a (LPA) Mouse Monoclonal Antibody [Clone ID: 8F6A9]
Other products for "LPA"
Specifications
Product Data | |
Clone Name | 8F6A9 |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of LPA (1823-2013 aa) expressed in E. Coli |
Specificity | Recognizes LPA, Lipoprotein, Lp(a) |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | lipoprotein(a) |
Database Link | |
Background | Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/gp 330. Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation. |
Synonyms | Apo(a), LPA |
Reference Data |
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