SRC Mouse Monoclonal Antibody [Clone ID: 5D10C4]

CAT#: AM06238SU-N

SRC mouse monoclonal antibody, clone 5D10C4, Ascites

Product Images

Western blot analysis using SRC mouse mAb against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).

Specifications

Product Data

• Clone Name: 5D10C4
• Applications: WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blotting: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.
• Specificity: Recognizes SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian).
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: SRC proto-oncogene, non-receptor tyrosine kinase
• Database Link:
  Entrez Gene 6714 Human
  UniProt ID P12931
• Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
• Synonyms: c-Src, pp60c-src