Pdcd1 Rat Monoclonal Antibody [Clone ID: RMP1-30]

CAT#: AM05572PU-L

Pdcd1 rat monoclonal antibody, clone RMP1-30, Purified

Specifications

Product Data

• Clone Name: RMP1-30
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 10⁶ cells in 100 µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: PD-1 transferred BHK cells
• Specificity: This antibody recognises CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified IgG
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: programmed cell death 1
• Database Link:
  Entrez Gene 18566 Mouse
  UniProt ID Q02242
• Background: CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes.
  Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.
• Synonyms: Protein PD-1, hPD-1, PDCD1